The questions in this quiz have been provided by Dr. Dominic Palazzolo, PhD.
Physiology Professor at LMU-DCOM
Gastrointestinal Physiology Quiz
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Question 1 |
A 45 year old woman presents with dysphagia (difficulty in swallowing) for solid foods and liquids. A barium swallow reveals dilation of the proximal esophagus, and a beak-like tapering of the distal esophagus. You correctly diagnosis achalasia and fully expect to see all of the following characteristics EXCEPT:
increased tone in the lower esophageal sphincter (LES) | |
absence of a coordinated peristaltic effort down the esophagus | |
nonfunctional or absence of the esophageal intramural plexuses (i.e. ENS) | |
decreased amounts of skeletal muscle along the upper third of esophagus | |
simultaneous low pressure increases along the entire length of the esophagus during a swallow |
Question 2 |
Which of the following secretagogues or conditions is most likely to stimulate the secretion of cholecystokinin (CCK) from the duodenal mucosa?
amino acids | |
free fatty acids | |
glucose | |
high pH | |
hypotonicity |
Question 3 |
What is the most common type of motility associated with the descending colon?
haustrations | |
antipropulsive movements | |
mass movement | |
perisatalsis | |
segmentation |
Question 4 |
You have sat down to a scrumptious meal consisting of a spinach salad, a juicy piece of very lean filet mignion (16 oz.), a baked potato with generous gobs of butter and sour cream, and a fine glass of a robust wine. Which of the following represents the BEST order in which the above items are sequentially emptied from the stomach?
fillet mignion, potato, wine, butter | |
wine, filet mignion, potato, butter | |
potato, filet mignion, butter, wine | |
wine, potato, filet mignion, butter | |
potato, wine, butter, filet mignion |
Question 5 |
Myenteric oscillation potentials are characterized as__________ slow waves which are ____________ likely to generate spontaneous action potentials.
High amplitude & low frequency - Less | |
High amplitude & low frequency - More | |
Low amplitude & high frequency - Less | |
Low amplitude & high frequency - More |
Question 6 |
Below is a list of events that occur during the act of vomiting.
- the LES and UES are open
- forced inspiration against a closed glottis
- reverse peristalsis from the mid small intestine
- the LES is open and the UES is closed
- relaxation of the pyloric sphincter
- forceful contractions of the stomach
Indicate the correct sequence of events involved in the act of vomiting
5, 3, 2, 6, 4, 1 | |
3, 5, 6, 2, 1, 4 | |
3, 5, 2, 6, 1, 4 | |
5, 3, 6, 2, 1, 4 | |
3, 5, 2, 6, 4, 1 |
Question 7 |
Which gastrointestinal function IS NOT caused by cholecystokinin?
contraction of the bladder | |
increased rate of gastric emptying | |
increased secretion of pancreatic juice rich in digestive enzymes | |
potentiation of secretin-induced pancreatic secretion rich in bicarbaonate | |
potentiation of secretin-induced bile production |
Question 8 |
Which of the following IS NOT a function of hepatocytes?
active uptake of plasma bile acids | |
synthesis of primary bile acids from cholesterol | |
conjugation secondary bile acids | |
conversion of bilirubin to urobilinogen | |
secretion of bile acids into bile canaliculi |
Question 9 |
Which cells type is PROPERLY matched with its secretion?
Enteroendocrine cell - Trypsinogen | |
Chief cell - Intrinsic factor | |
Parietal cell – Gastrin | |
G-cell - Pepsinogen | |
Enterochromaffin-like cell - Histamine |
Question 10 |
parotid gland | |
pancreatic | |
gastric | |
hepatic |
Question 11 |
By which mechanism of action does Cimetidine inhibit gastric acid secretion?
competing for the H2 receptor | |
competing for the M3 receptor | |
competing for the CCK-B/Gastrin receptor | |
blocking Ca4 channels | |
inhibiting the proton-pump |
Question 12 |
How does the autonomic nervous system affect salivary secretory rate?
Salivary secretory rate is increased in response to parasympathetic and sympathetic stimulation. | |
Salivary secretory rate is decreased in response to parasympathetic and sympathetic stimulation. | |
Salivary secretory rate is increased in response to parasympathetic stimulation and decreased in response to sympathetic stimulation. | |
Salivary secretory rate is decreased in response to parasympathetic stimulation and increased in response to sympathetic stimulation. |
Question 13 |
The transport of which substance IS NOT Na+-dependant?
glucose | |
fructose | |
galactose | |
proline | |
tryptophan |
Question 14 |
Which bond is cleaved by the action of isomaltase?
α-1, 4 glycosidic bonds of maltose | |
α-1, 6 glycosidic bonds of α-limiting dextrins | |
α-1, 6 glycosidic bonds of maltriose | |
β-1,,4 glycosidic bond of trehalose | |
β-1, 6 glycosidic bond of lactase |
Question 15 |
Excessive absorption of which substance is responsible for hemochromatosis?
iron | |
copper | |
magnesium | |
calcium | |
zinc |
Question 16 |
A 38 year old male walks into your office complaining of abdominal pain. An upper GI series revealed the presence of a gastric ulcer. Gastrin levels are 74 pg/ml (normal range is 50 to 150 pg/ml). Hydrochloric acid levels are 2mmoles/hr (normal range is 1 to 5 mmoles/hr). Blood analysis reveals elevated levels of macrophages and other immunocytes. From the given information, this individual is most likely suffering from ___________ which is best treated with__________.
Chronic Superficial Gastritis - antibiotics | |
Crohns*s Disease - somatostatin | |
Celiac Disease - opiates | |
H. Pylori infection - omeprazole | |
Gluten enteropathy - ipecac |
