Endocrine Physiology Quiz, part 1

Quiz questions provided by Dr. Dominic L. Palazzolo, PhD Professor of Physiology, LMU-DCOM
1. Insulin __________ phosphorylase and glucagon __________ phosphoenol pyruvate carboxykinase.

2. A deficiency in 1, 25-(OH)2-D3 (the active form of vitamin D) will lead to __________ osteoid production and a deficiency in parathyroid hormone will lead to __________ neuromuscular excitability.

3. Fasting will lead to __________ growth hormone secretion and _________ free somatomedin levels.

4. Excessive production of thyroxine will lead to __________ muscle mass and __________ appetite.

5. Cortisol acts to __________ glycogenesis and __________ gluconeogenesis.

6. Leptin acts to __________ appetite and melatonin acts to __________ the propensity for sleep.

7. Testosterone acts to __________ production of high density lipoproteins and estradiol acts to __________ bone resorption.

8. An XO female (Turner’s syndrome) has __________ Wolffian ducts and __________ Mullerian ducts.

9. Estradiol will act to __________ spinnbarkeit and progesterone will act to __________ cervical mucous ferning.

10. Using the following list of events concerning the fate of ingested iodine as it pertains to thyroid hormone synthesis, indicate the proper sequence of events.

  1. Endocytosis
  2. Incorporation
  3. Oxidation
  4. Recycling
  5. Reduction

11. Using the following list of events concerning the JAK-STAT signal transduction pathway, indicate the proper sequence of events.
  1. Formation of STAT dimers
  2. Ligand (i.e hormone) binds to receptor
  3. JAK binds to receptor
  4. JAK phosphorylates STAT
  5. Induction of nuclear transcription factors

12. Using the following list of enzymes, indicate the proper sequence in the synthesis of catecholamines.
  1. Dopamine-β- hydroxylase
  2. Dopa decarboxylase
  3. Phenylethanolamine - N - methyltransferase
  4. Tyrosine hydroxylase

13. Starting with cholesterol, indicate the proper enzyme sequence in the synthesis of testosterone.
  1. 3-β-ol-dehydrogenase
  2. 17-hydroxylase
  3. 17-β-OH-steroid dehydrogenase
  4. 17- 20-desmolase
  5. 20, 22-desmolase

14. Using the following list of events, indicate the proper sequence concerning the ovarian/uterine cycle.
  1. High levels of estradiol
  2. High levels of estradiol and progesterone
  3. Luteinizing Hormone (LH) surge
  4. Menstruation
  5. Presence of a corpus albicans