Endocrine Physiology Quiz, part 3

33. Which of the following hormones would you expect to circulate in blood bound to a transport protein?

adrenocorticotropin (ACTH)
antidiuretic hormone (ADH)
dihydroepiandrosterone (DHEA)
parathyroid hormone (PTH)
somatostatin

34. Which of the following is a description of a long loop feedback system?

cortisol inhibiting adrenocorticotropin hormone (ACTH)
growth hormone releasing hormone (GHRH) inhibiting it’s on release
prolactin stimulating dopamine release
somatomedin stimulating somatostatin
thyroid stimulating hormone (TSH) inhibiting thyrotropin releasing hormone (TRH)

35. Which of the following hormones would you expect to contribute towards a negative nitrogen balance?

cortisol
estrogen
growth hormone
insulin
testosterone

36. Insulin secretion from pancreatic β-cells can be stimulated by all the following means EXCEPT:

cholinergic activation of the pancreatic β- cell
closing or inhibiting of potassium channels on the pancreatic β- cell
increased entry of glucose into the pancreatic β- cell
paracrine action of glucagon (from pancreatic α-cells) on the pancreatic β- cell
stimulation of α2-adrenergic receptors on the pancreatic β- cell

37. Which of the following kinases is inhibited by insulin?

glucokinase
phosphoenolpyruvate carboxykinase
phosphofructose kinase
pyruvate kinase

38. Which of the following metabolic pathways is stimulated by glucagon?

gluconeogenesis
glycolysis
glycogenesis
lipogenesis

39. Glucagon initiates it action by __________.

binding to a nuclear receptor and activating the glucagon regulatory element (GRE)
binding to a receptor associated tyrosine kinase
binding to a tyrosine kinase
increasing intracellular production of cAMP
increasing intracellular production of IP3 and DAG

40. An increase in the insulin to glucagon ratio __________.

is observed during severe exercise
stimulates gluconeogenesis
stimulates glycogenolysis
will increase the amount of fructose-6-phosphate
will increase the amount of fructose-2, 6-bisphosphate

41. Which of the following genes are repressed by the active form of Vitamin D?

1-hydroxylase
alkaline phosphatase
calbindins
osteocalin
vitamin D nuclear receptor

42. The primary action of 1,25-(OH)2-D3 is to stimulate __________.

absorption of calcium from the gut
osteoclastic activity in the bone
osteocytic osteolysis in the bone
reabsorption of calcium from the kidney

43. Parathyroid hormone (PTH) levels are highest when intracellular levels of __________.

ATP and calcium are both high
ATP and calcium are both low
ATP is high and intracellular levels of calcium are low
ATP is low and intracellular levels of calcium are high

44. Parathyroid hormone acts to __________.

inhibit the reabsorption of calcium and phosphate from the kidney tubules
stimulate the reabsorption of calcium and phosphate from the kidney tubules
inhibit the reabsorption of calcium and stimulate the reabsorption of phosphate from the kidney tubules
stimulate the reabsorption of calcium and inhibit the reabsorption of phosphate from the kidney tubules

45. Which of the following second messengers is CORRECTLY matched with the actions of antidiuretic hormone (ADH)?

cyclic AMP - vasoconstriction
cyclic GMP - increase permeability of the collecting duct to water
diacylglyceride (DAG) - vasodilation
inositoltriphosphate (IP3) - stimulation of adrenalcorticotropin (ACTH) secretion

Endocrine Physiology Quiz, part 3

Quiz questions provided by Dr. Dominic L. Palazzolo, PhD Professor of Physiology, LMU-DCOM