Endocrine Physiology Quiz, Part 4

46. Oxytocin __________.

circulates in blood bound to neurophysin 1
is mainly produced in the supraoptic nucleus
is required for milk “let down”
stimulates lactogenesis
stimulates contraction of the endometrial cells of the uterus

47. Plasma levels of growth hormone are highest during__________.

adult life
birth
childhood
old age
puberty

48. Prolactin actions include all the following EXCEPT:

galactopoeisis
increased transcription of enzymes involved in lactose synthesis
increased transcription of milk protein
stimulation of gonadotropin secretion
stimulation of breast development

49. The action of 5-deiodinase in peripheral tissue will most likely yield __________.

reverse thyroxine (rT4)
reverse triiodothyronine (rT3)
thyroxine (T4)
triiodothyronine (T3)

50. Thyroid peroxidase is directly inhibited by __________.

low levels of plasma iodine
oubain
perchlorate
propylthiouracil (PTU)
thiocyanate

51. The triiodothyronine (T3) nuclear receptor activates the thyroid regulatory element (TRE) as a dimer with __________.

a heat shock protein
a thyroxine (T4) nuclear receptor
an RXR nuclear receptor for 9-cis-retinoic acid
another T3 nuclear receptor
transthyretin

52. An aldehyde at position C-18 will make a steroid into a more potent__________.

androgen
estrogen
glucocorticoid
progesterone
mineralocorticoid

53. Aldosterone synthase is produced in the __________.

zona fasicularis only
zona glomerulosa only
zona reticularis only
zona fasicularis and the zona glomerulosa
zona fasicularis, the zona glomerulosa, and the zona reticularis

54. Adrenoxin is __________.

a biogenic amine
a hormone produced by the kidneys
a required protein for the conversion of cholesterol to pregnenolone
a steroid synthesized in the liver
another name for P450scc

55. All of the following terms accurately describe the glucocorticoids EXCEPT:

anti-inmflamatory
anti-pyretic
immunosupressive
lactogenic
somnogenic

56. Which of the following actions would you attribute to epinephrine (EPI) following activation of the sympathetic division of the autonomic nervous system?

decreased activity of hormone sensitive adipose tissue lipase (HSATL)
decreased peripheral conversion of thyroxine (T4) to triiodothyronine (T3)
increased glucose uptake by myocytes
increased production of glucose by the liver
increased production of glucose by the liver

57. You expect epinephrine (EPI) to __________.

circulate in blood bound to a transport protein
be lipid soluble
be synthesized by mRNA directed protein synthesis
bind to β-receptors with greater affinity than to α-receptors
have a long half life

58. Which of the following profiles would you expect to see after three days of fasting?

a
b
c
d
e

59. Melatonin __________.

is derived from the amino acid tyrosine
is stored in secretory granules within pinealcytes
levels in plasma are higher during exposure to light as compared to exposure to dark
secretion is under sympathetic control
stimulates melanocytes to secrete melanin

60. Which of the following hormones IS NOT derived from proopiomelanocortin (POMC)?

adrenocorticotrophin (ACTH)
corticotrophin releasing hormone (CRH)
α-melanocyte stimulating hormone (MSH)
β-endorphin
β-lipotrophin

Endocrine Physiology Quiz, Part 4

Quiz questions provided by Dr. Dominic L. Palazzolo, PhD Professor of Physiology, LMU-DCOM